Laser Light Engine Output Stability Characterization

Abstract number
124
Presentation Form
Poster
DOI
10.22443/rms.elmi2024.124
Corresponding Email
[email protected]
Session
Poster Session
Authors
Iain Johnson (1), Andrii Repula (1), Claudia Jaffe (1)
Affiliations
1. Lumencor, Inc.
Abstract text

Laser Light Engines consisting of as many as eight independently operable solid-state lasers merged

into a common optical train, provide a compact and operationally efficient illumination solution for

applications requiring rapid and reproducible switching between different output wavelengths. Shared

environmental and electronic control infrastructure is designed to produce consistent spatial and

temporal light output characteristics among the numerous elements of the laser array, wherein only

wavelengths remain as the lone variable. This presentation describes characterization of both continuous

and pulsed light output from the seven lasers of CELESTA Light Engines, over different timescales and

using a variety of photometric detectors. Temporal output stability over timescales from milliseconds to

days is critical for applications of the CELESTA Light Engine. For example, smFISH imaging protocols for

identification of thousands of transcripts across 1 cm2 tissue specimens may extend for more than 24

hours. Furthermore, these image acquisition protocols typically utilize sequential illumination from four or

more of the seven lasers. Therefore, it is essential that the temporal characteristics of the laser sources

are consistent.