Carl Zeiss Microscopy
Chris Power1, Ed Rea2
1Carl Zeiss Microscopy GmbH, Germany. 2Carl Zeiss Ltd, United Kingdom
Workshop Room 11A
Understanding dynamic behaviour is vital to gaining insights into biological processes. Across all scales, dynamics provide a crucial insight, from movement of organisms, organs or cells, developmental changes in organisms or tissues to cell-cell interactions and intracellular molecular behaviour which one often cannot observe due to phototoxicity, slow acquisitions or too complicated software. ZEISS offers a wide range of systems & software to observe & analyse samples with minimal light exposure at high speed down to molecular resolution.
The ZEISS Lattice SIM super-resolution technology has taken research beyond the diffraction limit of conventional microscopy, giving you gentle super-resolution imaging with incredibly high speed and the ability to image deeper into challenging samples beyond 120 nm. Lattice SIM2 uses a 2D Lattice pattern that only requires translation, no rotation, for improved speed and higher contrast for deeper penetration into samples. SIM Apotome mode uses 2D striped illumination also without rotation for ultra-fast, exceptional optical sectioning. In combination with our SIM² reconstruction algorithm, both technologies keep pushing SIM to a new level.
Technology that enables imaging the details of biological samples with super-resolution is great, but each application comes with specific challenges and requirements, for example: imaging speed to capture dynamics, large fields of view and excellent 3D capabilities for contextual imaging of larger samples, sensitivity to image delicate samples, or resolution at the edge of what's physically possible to reveal subcellular ultrastructure.
If you wish you could meet these requirements for each of your samples in the best possible way, while remaining flexible across scales, then join us at elmi2024 to be introduced to a new family of ZEISS imaging systems that will allow you to reveal cellular behavior and inter-cellular dynamics, the vibrant sub-organelle network of life, and life across scales-down to molecular details.