Chip NanoImaging
Merete Storflor, Øystein Helle, Jon Kristian Hagene
Workshop Room 20
The diversity of your biological processes can be captured with chip-based TIRF microscopy. Chip NanoImaging provides precise optical sectioning over an ultra-large field of view. The imaging platform allows for both live- and fixed- cell imaging. Using multimode waveguide technology, a well-defined and homogeneous TIRF illumination can be generated. This is particularly well-suited for exploring membrane dynamics and drug-interactions.
Chip NanoImaging provides a complete microscope system with both TIRF and EPI illumination. It also comes with a software package that enables contrast enhancement for both 2D (TIRF), and 3D (EPI) imaging. During the workshop, we will demonstrate that the ultra-large field of view chip-based TIRF is ideal for both diffraction limited as well as super-resolution microscopy using single molecule localization microscopy (SMLM). We will also demonstrate how the large SMLM datasets are efficiently reconstructed with user-friendly GPU-accelerated post-processing software.
